视网膜静脉周围炎玻璃体取出物细胞学研究

摘要

To study the pathcytological mechanism of Eales disease and to provide a histological testimony for an effictive therapy.Methods45 cases(48 eyes) of Eales disease that were diagnosed according to vitreous hemorrhage and proliferative vitreoretinopathy or secondary retinal detachment.Cytomorphological examination was taken and vitreous extracts were examined by immunohistochemical staining.ResultLymphocytes and fibroblastes were most of those cells in the vitreous extracts.Immunohistology and electron microscopy revealed that lymphocytes were 78.8% or 61.5% in all specimens,respectively.ConclusionProliferative vitreoretinopathy induced by Eales disease closely relates with lymphocytes.The results suggested that autoimmunity might play an important role in the pathogenic mechanism of the disease%目的　视网膜静脉周围炎的细胞学研究目的　在于探讨其发病原因发展过程及其在病理细胞学方面的机制,为寻求行之有效的治疗。方法　提供组织学依据。方法　临床确诊为视网膜静脉周围炎,玻璃体出血伴增生性玻璃体视网膜病变或继发视网膜脱离者45例(48只眼)。结果　玻璃体取出物细胞例数为淋巴细胞和成纤维细胞占首位免疫组化染色及电镜证实检出的淋巴细胞中T淋巴细胞分别占78.8%和61.5%。结论　　视网膜静脉周围炎引起的增生性玻璃体视网膜病变与T淋巴细胞密切相关,提示自身免疫反应在发病机理中可能起了一定作用