首页> 中文期刊> 《疑难病杂志》 >低温等离子消融联合利鼻脱敏汤治疗持续性变应性鼻炎疗效观察

低温等离子消融联合利鼻脱敏汤治疗持续性变应性鼻炎疗效观察

             

摘要

Objective To evaluate the effect of Libituomin soup ( LBTMS ) on perennial allergic rhinitis ( PAR ) as a post-operative combined therapy during treatment with low temperature plasma ablation ( LTPA ). Methods The enrolled patients ( n = 223 ) were divided into two groups, treatment group ( n = 125 ) received LTPA and intake of LBTMS for 14 days and the control group ( n = 98 ) of patient received LTPA alone. The clinical symptom ( VAS score ) and quality of life evaluation ( RQLQ score ) were earned out after two years. Results Both groups of patients showed clinical relief and improvement of quality of life after these treatments. VAS score from 30. 53 ±2. 27 to 16. 50 ±5. 02 in control group, from 31. 43 ±2. 42 to 13. 34 ±6. 17 in treatment group ( P < 0. 05 ); RQLQ score from 61. 00 ± 20. 52 to 29. 05 ± 8. 64 in control group, from 60. 67 ± 22. 30 to 26. 08 ± 9. 72 in treatment group ( P < 0. 05 ). LTPA and LBTMS group had superior therapeutic effect over LTPA alone group with statistically significant difference( P < 0. 05 ). Conclusion Combination of LTPA and LBTMS on the treatment of PAR shows better effect over surgical procedure alone.%目的 探讨低温等离子消融联合利鼻脱敏汤治疗持续性变应性鼻炎(PAR)的疗效.方法 223例PAR患者随机分成2组,治疗组125例给予低温等离子消融术治疗,并联合应用中药利鼻脱敏汤,7 d为1个疗程,服用2个疗程;对照组98例仅给予低温等离子消融治疗.2年后评估临床症状(VAS评分)和生活质量(RQLQ评分)变化.结果 2组治疗后临床症状和生活质量均有明显改善,对照组VAS评分由治疗前的(30.53±2.27)分降至(16.50±5.02)分,治疗组由(31.43±2.42)分降至(13.34±6.17)分,差异有统计学意义(P<0.05);对照组RQLQ评分由治疗前的(61.00±20.52)分降至(29.05±8.64)分,治疗组由(60.67±22.30)分降至(26.08±9.72)分,差异有统计学意义(P<0.05).且治疗组均优于对照组(P<0.05).结论 低温等离子消融术联合利鼻脱敏汤治疗PAR疗效明显优于单纯手术治疗.

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