Objective To investigate the effect of sleep quality on the blood glucose level in elderly patients with dia -betes and correlation between depression and sleep quality .Methods From 2011 October to 2012 October, 75 cases of elder-ly diabetic patients with sleep disorders were enrolled and they were randomly divided into study group and control group , 38 patients in the study group were treated with sleep intervention , 37 cases in the control group did not give sleep intervention , fasting blood glucose (FPG), 2 h postprandial blood glucose (2 hPG), glycosylated hemoglobin (HbA1c) and fasting insulin (FIns) level, calculate the insulin resistance index (HOMA-IR) were measured before and after treatment , 2 groups of pa-tients were compared with Pittsburgh sleep quality index (PSQI) score, Hamilton depression scale (HAMD) score, and eval-uate the relationship between PSQI and HAMD scores in these patients .Results No statistical significance of FPG and 2hPG, HbA1c, FIns and HOMA-IR were found before treatment between the 2 groups ( P >0.05).After treatment, these indexes were significantly improved compared with before treatment in the 2 groups, the difference was statistically significant ( P <0.05);and the study group improved significantly than in the control group , the difference was statistically significant ( P <0.05).Before treatment, 2 groups of patients'PSQI, HAMD scores did not show statistically significant ( P >0.05), com-pared with before treatment, after treatment, the control group's PSQI, HAMD scores were not statistically significant (P >0.05), the study group was significantly reduced ( P <0.05), and the study group was superior to control group (P <0.05).PSQI scores were positively correlated with HAMD score ( r =0.695, P <0.05).It has effect on the blood glucose level.Conclusion Sleep disorders has effect on the level of blood glucose in elderly diabetic patients ;there was a significant correlation between the degree of depression and sleep quality .%目的：探讨睡眠质量对老年糖尿病患者血糖水平的影响及其与抑郁状态的相关性。方法选择2011年10月-2012年10月合并睡眠障碍的老年糖尿病患者75例，按照数字表法随机分为研究组和对照组，研究组38例给予睡眠干预，对照组37例未给予睡眠干预，分别测定患者治疗前、后的空腹血糖（FPG）、餐后2 h血糖（2 h PG）、糖化血红蛋白（HbA1c）及空腹胰岛素（FIns）水平，计算胰岛素抵抗指数（HOMA-IR），比较2组患者匹兹堡睡眠质量指数量表（ PSQI）评分与汉密尔顿抑郁量表（ HAMD）评分，并评估患者PSQI与HAMD评分的相关性。结果治疗前2组患者FPG和2 hPG、HbA1c、FIns以及HOMA-IR差异无统计学意义（ P ＞0@．05）。治疗后2组患者各指标较治疗前明显改善，差异有统计学意义（ P ＜0．05）；且研究组较对照组改善明显，差异有统计学意义（ P ＜0．05）。2组患者治疗前PSQI、HAMD评分差异无统计学意义（ P ＞0．05）；与治疗前比较，治疗后对照组PSQI、HAMD评分差异无统计学意义（ P ＞0．05），研究组明显减少（ P ＜0．05），且研究组优于对照组（ P ＜0．05）。 PSQI评分与HAMD评分呈正相关（ r ＝0．695， P ＜0．05）。结论合并睡眠障碍的老年糖尿病患者可影响血糖水平；睡眠质量的高低与抑郁程度存在明显相关。
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