Objective To investigate the choice of surgical methods of primary duodenal malignant tumor ( PDMT) and its therapeutic effect .Methods The clinical data of 65 patients with PDMT who were diagnosed and operated in the De-partment of gastrointestinal surgery , the Xinjiang Uygur Autonomous Region people's Hospital from July 2008 to June 2015 , were analyzed retrospectively .Results In 65 patients underwent radical pancreaticoduodenectomy resection of 40 cases, 1 case was lost to follow-up of 1 year, 3 years and 5 years survival rates of 32 cases (82.1%), 23 cases (59.0%), 13 cases (33.3%);local excision was performed in 5 cases, postoperative 1 year, 3 years and 5 years survival rates for the 3 cases (60.0%), 2 cases (40.0%), 1 cases (20.0%);the bypass surgery in 15 cases, postoperative 1 year, 3 years and 5 years survival were 8 cases (53.3%), 5 cases (33.3%), 1 cases (6.7%);5 cases received no surgical treatment of patients 1 year in all death .Conclusion PDMT was the first choice for radical resection of pancreatic and duodenal resection , followed by partial resection , and bypass surgery can improve the quality of life and prolong the survival time of patients .%目的：探讨原发性十二指肠恶性肿瘤（ PDMT）手术方式的选择及疗效。方法2008年7月—2015年6月新疆维吾尔自治区人民医院胃肠外科诊断和手术治疗PDMT患者65例，对其临床资料进行回顾性分析。结果65例患者中，行根治性胰十二指肠切除术40例，1例失访，术后1年、3年、5年生存分别为32例（82抖．1％）、23例（59．0％）、13例（33．3％）；局部切除术5例，术后1年、3年、5年生存分别为3例（60．0％）、2例（40．0％）、1例（20．0％）；旁路手术15例，术后1年、3年、5年生存分别为8例（53．3％）、5例（33．3％）、1例（6．7％）；5例未接受手术治疗患者在1年内全部死亡。结论 PDMT的术式选择以根治性胰十二指肠切除术为首选，其次为局部切除术，而旁路手术亦可改善患者的生存质量和延长生存时间。
展开▼
