人工牛黄甲硝唑胶囊联合云南白药治疗复发性口腔溃疡的临床观察

摘要

ObjectiveTo observe the effect of artificial cow-bezoar and metronidazole capsules combined with yunnan baiyao on the treatment of recurrent oral ulcer.Methods80 patients with recurrent oral ulcer were randomly assigned into treatment group and control group. The treatment group was treated by oral administration of artificial cow-bezoar metronidazole capsules and external use of Yunnan baiyao white powder, and the control group was treated by sublingual administration of cydiodine buccal tablets. The clinical curative effects and the av-erage healing, average symptoms disappear and average recurrence time were compared between these two groups. ResultsThe oral ulcer healed faster in the treatment group, the pain symptoms was obviously relieved, and the recurrence interval was extended. No adverse reaction was observed. The clinical curative effect was better than the control group(P<0.05). ConclusionThe artificial cow-bezoar metronidazole capsules combined with yun-nan baiyao had safe and effective effects on the treatment of recurrent oral ulcer by intemal and external use. It is worthy of further promotion and application in clinic.%目的：观察人工牛黄甲硝唑胶囊联合云南白药治疗复发性口腔溃疡的临床效果。方法选取复发性口腔溃疡患者80例，随机分成2组，观察组给予人工牛黄甲硝唑胶囊口服及云南白药粉外用，对照组给予华素片含服。比较2组的临床疗效及平均愈合、平均症状消失和平均复发时间。结果观察组经治疗后溃疡愈合快，疼痛症状缓解明显，复发间隔时间延长，无不良反应，优于对照组（P<0.05）。结论人工牛黄甲硝唑胶囊联合云南白药治疗复发性口腔溃疡，内服加外用安全且疗效显著，值得在临床上进一步推广和应用。