儿童早期严重龋与血红蛋白和微量元素水平的相关性调查

摘要

AIM:To investigate the relationship between serum hemoglobin and microelement levels in chi-dren with severe early childhood caries(S-ECC).METHODS:Among the 403 children enrolled in the study,88 were caries-free and 84 were with S-ECC.Serum hemoglobin level and serum iron,zinc,copper and lead concentra-tion were measured and compared between the 2 groups using SPSS 1 7.0 software.RESULTS:The hemoglobin level (g/L)of S-ECC and caries-free group was 122.8 ±8.5 and 125.3 ±8.7 respectively(P<0.05),the serum iron (mg/L)1 .06 ±0.43 and 1 .30 ±0.45 (P<0.05 ),zinc (mg/L)0.87 ±0.35 and 1 .08 ±0.34 (P<0.05 ),lead (μg/L)62.0 ±8.4 and 48.0 ±7.9(P<0.05),copper(mg/L)0.99 ±0.38 and 1 .04 ±0.36(P>0.05),respec-tively.CONCLUSION:Children wuth S-ECC have lower hemoglobin level,lower iron and zinc level and higher lead level,indicating poor nutritional status.%目的：调查儿童早期严重龋（S－ECC）与血红蛋白、血清微量元素水平之间的相关性。方法：选择3～5周岁儿童403名，其中分为无龋组（n＝88）和S－ECC组（n＝84）。检查两组儿童的血红蛋白浓度及血清铁、锌、铜、铅4项微量元素含量，并进行统计学分析。结果：S－ECC 组和无龋组儿童的血红蛋白浓度（g／L）分别为122．8±8．5、125．3±8．7（P＜0．05）；血清铁浓度（mg／L）分别为1．06±0．43、1．30±0．45（P＜0．05），锌浓度（mg／L）分别为0．87±0．35、1．08±0．34（P＜0．05），铅浓度（μg／L）分别为62．0±8．4、48．0±7．9（P＜0．05），铜浓度（mg／L）分别为0．99±0．38、1．04±0．36（P＞0．05）。结论：与无龋儿童相比， S－ECC 儿童血红蛋白、铁、锌偏低，血铅偏高，提示其全身营养状况应引起重视。