Al(H_2PO_4)_3 as an Efficient and Reusable Catalyst for One-pot Three-component Synthesis of α-Amino Phosphonates under Solvent-free Conditions

摘要

Synthesis of α-amino phosphonates is described under solvent-free conditions at 100 ℃ from reaction between aldehydes and amines in the presence of trialkyl phosphites using Al(H_2PO_4)_3 as an efficient and reusable heteroge-neous catalyst. The advantages of this procedure are short reaction time, flexibility and having high to excellent yields.