A Green Route for the One-Pot Synthesis of 1,2-Disubstituted Benzimidazoles Using Iron（Ill） Phosphate under Solventless Conditions

摘要

1,2-Disubstituted benzimidazoles are selectively synthesized in high yields under extremely mild conditions via the condensation of o-phenylenediamine derivatives with aldehyde derivatives using catalytic amount of iron（Ⅲ） phosphate under solventfree conditions. The use of readily available iron（Ⅲ） phosphate as a reusable and recyelable catalyst makes this process quite simple, convenient, and environment-friendly.