负性情绪对冠心病 PCI 手术患者预后的影响

摘要

Objective:To explore influence of negative emotions on prognosis of patients with coronary heart disease (CHD) after percutaneous coronary intervention (PCI) .Methods :Self‐rating anxiety scale (SAS) and self‐rating depression scale (SDS) were used to assess 90 patients undergoing PCI .According to the score results ,patients were divided into pure depression group (n=28 ,occupied 31.11% ) ,pure anxiety group (n=22 ,24.44% ) ,anxiety com‐plicated depression group (n= 25 ,27.78% ) and normal group (n = 15 ) . All patients were followed up for 12 months ,and Logistic regression analysis was used to analyze risk factors for major adverse cardiovascular events (MACE) .Results:Incidence rates of MACE in pure depression group ,pure anxiety group and anxiety complicated depression group were significantly higher than that of normal group (42.86% vs .40.91% vs .64.00% vs .6.67% , P<0.05 or <0.01) ,and that of anxiety complicated depression group was significantly higher than those of pure depression group and pure anxiety group (P<0.05 both) .Logistic regression analysis indicated that anxiety ,depres‐sion ,anxiety complicated depression were risk factors for MACE (OR = 1.49 ,2.16 ,3.28 , P < 0.05 or < 0.01) . Conclusion : Most patients undergoing coronary intervention possesses negative emotions ,which are risk factors for adverse clinical events and affect their prognosis .%目的：探讨经皮冠状动脉介入治疗（PC I ）术后冠心病患者负性情绪发生情况及其对预后的影响。方法：采用焦虑自评量表（SAS）和抑郁自评量表（SDS）对接受 PCI手术的90例患者进行评定，按照评分结果分为单纯抑郁组（28例，占31.11％）、单纯焦虑组（22例， 24.44％）、焦虑合并抑郁组（25例，27.78％）和正常组（15例）。对患者进行12个月的随访，采用Logistic回归分析主要不良心血管事件（MACE）的危险因素。结果：单纯抑郁组、单纯焦虑组、焦虑合并抑郁组患者 M ACE发生率显著高于正常组（42.86％比40.91％比64.00％比6.67％， P＜0.05或＜0.01）。焦虑合并抑郁组MACE发生率显著高于单纯焦虑组和单纯抑郁组（P均＜0.05）。Logistic回归结果显示焦虑、抑郁、焦虑合并抑郁是M ACE的危险因素（OR＝1.49、2.16、3.28， P＜0.05或＜0.01）。结论：大多数PCI术后患者存在负性情绪，负性情绪是发生不良临床事件的危险因素，影响患者预后。