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Long-term survival ofearly-stage non-small cell lung cancer patients who underwent robotic procedure:a propensity score-matched study

机译:接受机器人手术的早期非小细胞肺癌患者的长期生存:一项倾向得分匹配研究

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Background:In the past decade, many researchers focused on to robot‑assisted surgery. However, on long‑term outcomes for patients with early‑stage non–small cell lung cancer (NSCLC), whether the robotic procedure is superior to video‑assisted thoracic surgery (VATS) and thoracotomy is unclear. Nonetheless, in the article titled “Long‑term survival based on the surgical approach to lobectomy for clinical stage I non–small cell lung cancer: comparison of robotic, video assisted thoracic surgery, and thoracotomy lobectomy” by Yang etal. that was recently published in Annals of Surgery, the authors provided convincing evidence that the robotic procedure results in similar long‑term survival as compared with VATS and thoracotomy. Minimally invasive procedures typically result in shorter lengths of hospital stay, and the robotic procedure in particular results in superior lymph node assessment. Main body:Our propensity score‑matched study generated high‑quality data. Based on our ifndings, we see prom‑ise in expanding patient access to robotic lung resections. In this study, propensity score matching minimized the bias involved between groups. Nevertheless, due to its retrospective nature, bias may still exist. Currently, the concept of rapid rehabilitation is widely accepted, and it is very diffcult to set up a randomized controlled trial to compare robotic, VATS, and thoracotomy procedures for the treatment of NSCLC. Therefore, to overcome this limitation and to minimize bias, the best approach is to use a registry and prospectively collected, propensity score‑matched data. Conclusions:Robotic lung resections result in similar long‑term survival as compared with VATS and thoracotomy. Robot‑assisted and VATS procedures are associated with short lengths of hospital stay, and the robotic procedure in particular results in superior lymph node assessment. Considering the alarming increase in the incidence of lung can‑cer in China, a nationwide database of prospectively collected data available for clinical research would be especially important.
机译:背景:在过去的十年中,许多研究人员专注于机器人辅助手术。但是,对于早期非小细胞肺癌(NSCLC)患者的长期结果,机器人程序是否优于视频胸腔镜手术(VATS)和开胸手术尚不清楚。尽管如此,Yang等人在题为“基于肺叶切除术的手术方法的临床I期非小细胞肺癌的长期生存:机器人,电视胸腔镜手术和开胸肺叶切除术的比较”的文章中。作者最近发表在《外科年鉴》上,作者提供了令人信服的证据,表明与VATS和开胸手术相比,机器人手术可实现相似的长期生存。微创手术通常会缩短住院时间,而机器人手术尤其会导致更好的淋巴结评估。 主体:我们的倾向得分匹配研究产生了高质量的数据。根据我们的发现,我们看到扩大患者进入机器人肺切除术的承诺。在这项研究中,倾向得分匹配将各组之间的偏见最小化。但是,由于其追溯性质,可能仍然存在偏见。目前,快速康复的概念已被广泛接受,建立一个随机对照试验来比较机器人,VATS和开胸手术治疗非小细胞肺癌的方法非常困难。因此,为了克服此限制并最大程度地减少偏差,最好的方法是使用注册表和前瞻性收集的,倾向得分匹配的数据。 结论:与VATS和开胸手术相比,机器人肺切除术具有相似的长期生存率。机器人辅助和VATS程序与住院时间短有关,尤其是机器人程序可带来更好的淋巴结评估。考虑到中国肺癌的发病率惊人地增加,全国范围内可用于临床研究的前瞻性收集数据的数据库将尤其重要。

著录项

  • 来源
    《癌症(英文版)》 |2016年第007期|339-341|共3页
  • 作者

    Hao-Xian Yang;

  • 作者单位

    Department ofThoracic Surgery, State Key Laboratory of0ncology inSouth China, Colaborative Innovation Center forCancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou510060, Guangdong, P. R. China;

  • 收录信息 北京大学中文核心期刊目录(北大核心);中国科学引文数据库(CSCD);中国科技论文与引文数据库(CSTPCD);
  • 原文格式 PDF
  • 正文语种 eng
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