Department of Pathology;
Cancer Hospital;
Shanghai Medical University;
Laboratory of Dermatopathology;
Huashan Hospital;
Shanghai Medical University;
Laboratory of Dermatopathology;
Huashan Hospital;
Shanghai Medical Universityhe present work studied the application of AgNOR count to differential diagnosis between cutaneous T cell lymphoma (CTCL) and cutaneous pseudolymphoma (CPL). Paraffin sections from 50 mycosis fungoides (22 MFI-Premycotic stage;
24 MF Ⅰ infiltrative stage and 4 MF Ⅲ - tumor stage);
2 nonepidermotropic cutaneous T cell lymphoma (NECTCL) and 9 CPL were investigated. In each case;
200 cells randomly selected were examined using a × 100 oil immersion lens. The mean number;
standard deviation and standard error of the mean of AgNOR counts were as follows: MFⅠ 1.17±0.09;
SEM = 0.01;
MⅡ 1.17±0.01;
SEM = 0.01;
MF Ⅲ. 3.55±0.87;
SEM = 0.43;
NECTCL 4.5±0.28;
SEM -0.199;
CPL 1.17±0.1;
SEM ± 0.03. The results revealed a highly significant difference between CTCL (MFⅢ+NECTCL) and CPL (t = 4.75;
P<0.001);
tumor stage (MF Ⅲ) and pretumor stage (MFI;
MF Ⅱ) of mycosis fungoides (t = 4.75;
P<0.001). Thus. AgNOR count is valuable in differential diagnosis.;
deviation; sections; CELL; heterogeneity; immersion; counts; valuable; sometimes; aggregate; nodule;