THE HBx PROTEIN EXPRESSION IN LIVER CANCER

摘要

The expression of HBx protein in liver tissues from 48 cases of different liver diseases, Including 32 cases of hepatocellular carcinoma (HCC), 10 of chronic hepatitis (CH), 2 of angioma and 4 cases of normal liver was studied. These samples were tested for HBx protein, HBsAg by modified ABC method. Positive rates of HBx in cancer and adjacent Uver tissue were 75. 0% and 62. 5%, and positive rates of HBsAg were 37.5% and 78.1% respectively. The occurence of HBx in the absence of HBsAg was more frequently observed in tissues from HCC (46.9%) man CH (0%). The results showed mat expression of HBx was more active than that of HBsAg, and it Is suggested that HBx might be a useful marker for the diagnosis of liver cancer.