BONE-INDUCING ABILITY OF BONE MORPHOGENETIC PROTEIN (BMP) BOUND TO BIO-CERAMIC IMPLANTS:EXPERIMENTAL OBSERVATION AND CLINICAL APPLICATION

摘要

Bone morphogenetic protein (BMP)is an efficient bone-inducing protein whichmainly exists in bone matrix.The implants of Bovine BMP (bBMP)extracted frombovine bone matrix can induce differentiation of mesenchymal cells of mice muscle in-to chondroand osteo-cytes and form new bone further.In order to evaluate im-plantable biomaterial that possesses not only osteogenic ability,but also stengtn,