Objective To observe the clinical efficacy and relapse rate of the 5-aminolevulinic acid photodynamic therapy(ALA -PDT) for squamous cell carcinoma. Methods 30 patients with squamous cell carcinoma diagnosed byhistopathological examination were treated by ALA-PDT for 4 to 11 times,and comparied with those patients who weretreated by surgery for a relapse rate. Results The complete remission were achieved in 29 patients from treatmentgroup, and that were considered up to clinical cure. After 6 to 12 month follow-up, 4 cases from treatment group and 5cases from control group were found to relapse, there was no statistical significant difference (P ＞0.05).However,satisfactory cosmetic results were achieved in treatment group by ALA -PDT.Conclusion For those patients withcutaneous squamous cell carcinoma,especially for elderly ones, the recurrence rate of ALA-PDT was similar to that ofsurgical methods,but ALA-PDT had the advantage of less damage and better cosmetic results.%目的:观察5-氨基酮戊酸光动力疗法(ALA-PDT)治疗皮肤鳞状细胞癌的临床疗效和复发率.方法:对30例经组织病理学确诊的皮肤鳞状细胞癌进行了4～11次ALA-PDT治疗,并与经手术治疗的30例患者进行复发率的比较.结果:治疗组29例患者获完全缓解,临床治愈.经6～12月随访后,4例复发;对照组5例复发,统计学处理无显著性差异(P＞0.05).但光动力组美容效果满意.结论:对皮肤鳞状细胞癌尤其老年患者,ALA-PDT疗法损伤小、美容效果好,复发率与手术方法相当(P＞0.05).
展开▼
