Preventive antibiotics using status of 1148 cases of surgical patients who had no significant infective symbols in a general tertiary hospital were surveyed. There was no significant different on combined antibiotics using between type Ⅰ incision and type Ⅱ incision (P>0.05, X2=3.11). Antibiotic using over 3 days in group of type Ⅰ incision was significant higher than type Ⅱ incision ( P<0.05, X2=4.47 ) . Non-rational antibiotics using is existence.%对某大型综合性医院无明显感染征象的1148例手术病人围术期预防性使用抗菌药物进行调查分析,显示Ⅰ类切口与Ⅱ类切口联合用药的比例无显著差异(P>0.05,X2=3.11),用药大于3天的Ⅰ类切口比例显著高于Ⅱ类切口(P<0.05,X2=4.47),存在不合理用药现象.
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