A new coumarin glucoside ester from seeds oil leavings of Xanthoceras sorbifolia

摘要

Objective: To study the coumarin from the seeds oil leavings of Xanthoceras sorbifolia.Methods: The chemical constituents were isolated and purified by combination of silica gel, macroporous resin, Sephadex LH-20, and ODS column chromatography. Their structures were elucidated by spectral and chemical methods. The cytotoxicity of the new compound against 10 selected human cancer cell lines was assayed.Results: Five comarins were isolated and identified as fraxetin-7-O-β-D-[6’-(3''–hydroxyl–3''-methylglutaryl)] glucopyranoside(1), fraxoside(2), fraxetin(3), scopoline(4), and esculetin(5), respectively.Conclusion: Compound 1 is a new compound. Unfortunately, this compound exhibited no cytotoxicity with tested cell lines.