呼吸系统疾病合并糖尿病的临床特点研究

摘要

Objective To analyze the clinical characteristics of respiratory disease patients with complicated diabetes mellitus with the hope to improve the levels of diagnosis and treatment among these patients.Methods A total of 598 patients with respiratory diseases and complicated diabetes mellitus admitted to our hospital from July 2003 to July 2008 were enrolled to conduct a retrospective study.Results The incidence rate of complicated diabetes in patients with respiratory diseases increasedyear by year with statistical significance ( P ＜ 0.01 ).The incidence rate of of complicated diabetes in patients with respiratory diseases was higher in patients aged 60 and over ( P ＜ 0.01 ) and remained similar between genders ( P ＞0.05 ).Of all the respiratory disease patients with complicated diabetes , those with infectious respiratory diseases ranked first in number, accounting for 45.48％ of all; patients with COPD and bronchiogenic carcinoma ranked second and third respectively, accounting for 21.91％ and 12.71％ of all the comorbidity patients.Percentage of patients with normal glycosylated hemoglobin was lower in patients with complicated diabetes mellitus than in patients of simple diahetes mellitus ( P ＜ 0.05 ); meanwhile, percentage of increased urinary albumin in patients with complicated diabetes mellitus was higher than in patients with simple diabetes mellitus ( P ＜0.05 ).Conclusion The incidence of complicated diahetes in respiratory disease patients is increasing.Poor blood glucose control and complicated with diabetic nephropathy are among reasons for susceptibility of respiratory disease.Blood glucose should be monitored when dealing with respiratory diseases in these patients.%目的 分析呼吸系统疾病合并糖尿病患者的临床特点、治疗及预后,提高其诊断及治疗水平.方法 回顾性分析2003年7月-2008年7月于我院住院的呼吸系统疾病合并糖尿病患者598例.结果 呼吸系统疾病合并糖尿病的发生率呈逐年上升趋势,差异有统计学意义(P＜0.01),60岁以上人群高于60岁以下(含60岁)人群,差异有统计学意义(P＜0.01),性别间差异无统计学意义(P＞0.05);呼吸系统疾病合并糖尿病患者中,呼吸系统感染性疾病(45.48%)所占比例最高,慢性阻塞性肺疾病(COPD,21.91%)位居第二,支气管肺癌(12.71%)位居第三;呼吸系统疾病合并糖尿病患者糖化血红蛋白在正常范围的比例低于单纯糖尿病患者,差异有统计学意义(P＜0.05),尿微量清蛋白的发生率高于单纯糖尿病患者,差异有统计学意义(P＜0.05).结论 呼吸系统疾病合并糖尿病的发生率呈逐年上升趋势;血糖控制不佳及合并糖尿病肾病是糖尿病容易与呼吸系统疾病并存的主要原因;治疗呼吸系统疾病时应注意检测血糖.