东莞地区毛细支气管炎患儿病原学分析

摘要

Objective:To study the pathogenic distribution characteristics of children with bronchiolitis in Dongguan,and to provide a theoretical basis for clinical treatment.Method:329 cases of children with bronchiolitis were selected as the experimental group from May 2015 to May 2013 in the Fifth People’s Hospital of Dongguan,and 286 cases of children with bronchial pneumonia were selected as the control group in the same period,used direct immuno fluorescence method detecting seven kinds of common respiratory viruses,mycoplasma pneumonia and chlamydia pneumoniae,the results were conducted for statistical analysis.Result:126 cases(38.3%) were positived for respiratory syncytial virus in the experimental group,compared with the control group,it was statistically significant(P<0.01).The positive rates of MP,CP,ADV,IV-A,IV-B,PIV-1,PIV-2,PIV-3 were respectively 17%,8.2%,1.2%,2.4%,0.9%,0.6%, 0.3%,7.0% in the experimental group,there were no statistically significant(P>0.05).Conclusion:Respiratory syncytial virus is still the most common pathogen of capillary bronchitis,mycoplasma pneumonia and chlamydia pneumoniae have become the important pathogens of bronchiolitis.%目的：探讨东莞地区毛细支气管炎患儿的病原分布特点，为临床治疗提供理论依据。方法：选择东莞市第五人民医院2013年5月-2015年5月住院的329例毛细支气管炎患儿为试验组，以及同期的286例支气管肺炎患儿为对照组，采用直接免疫荧光法检测7种常见呼吸道病毒、肺炎支原体和肺炎衣原体，并对结果进行统计学分析。结果：试验组呼吸道RSV阳性126例(38.3%)，与对照组比较差异有统计学意义(P<0.01)。试验组MP、CP、ADV、IV-A、IV-B、PIV-1、PIV-2、PIV-3阳性率分别为17.0%、8.2%、1.2%、2.4%、0.9%、0.6%、0.3%、7.0%，与对照组比较差异均无统计学意义(P>0.05)。结论：呼吸道合胞病毒仍然是毛细支气管炎最常见的病原体，肺炎支原体、肺炎衣原体也已成为引起毛细支气管炎的重要病原体。