老年胆囊结石患者腹腔镜与开放手术应激反应的比较

摘要

Objective:To explore the stress reaction of laparoscopic and open operation in the treatment of elderly patients with cholecystolithiasis.Methods:72 cases of elderly patients with cholecystolithiasis were selected.They were divided into the laparoscope group and open operation group.We compared serum CRP concentration,cortisol,IL-6 and IL-10 concentration of the two groups.Results:In the laparoscope group,serum IL-6 concentration was lower than the open operation group;IL-10 was significantly higher than that in the open operation group;the concentration of CRP and cortisol concentration at the first day after operation were obviously lower than the open operation group(P<0.05).Conclusion:Laparoscopic surgery in the treatment of elderly patients with cholecystolithiasis had many advantages,such as small trauma,less pain,faster recovery and so on.Compared with open surgery,the postoperative stress reaction of patients was light,and it can be used as the first choice for elderly patients with cholecystolithiasis.%目的：探讨腹腔镜和开放手术对老年胆囊结石患者应激反应的影响。方法：收治胆囊结石老年患者72例，分为开腹组和腹腔镜组，比较两组患者的血清CRP浓度、皮质醇浓度、IL-6和IL-10浓度。结果：腹腔镜组的血清IL-6浓度低于开腹组，IL-10明显高于开腹组，CRP 浓度和术后第1天的皮质醇浓度明显低于开腹组(P＜0.05)。结论：腹腔镜手术治疗老年胆囊结石患者具有创伤小、痛苦小、恢复快等优点，患者的术后应激反应比开放手术轻，可以作为老年胆囊结石的首选手术方式。