Dimericbiscognienynes B and C: New diisoprenyl-cyclohexene-type meroterpenoid dimers from Biscogniauxia sp.

摘要

Dimericbiscognienynes B and C (1 and 2),two new diisoprenyl-cyclohexene-type meroterpenoid dimers,were isolated from Biscogniauxia sp.71-10-1-1.Their structures,including the absolute configurations,were determined by spectroscopic analyses and ECD experiments.Meroterpenoids are special natural products that originate from mixed terpenoid-nonterpenoid pathway.As a member of meroterpenoid family,diisoprenyl-cyclohexene/ane-type meroterpenoids composed of two isoprenyl chains (C5 unit)and a cyclohexene/ane moiety (C6 unit),featuring diverse skeleton structures with wide range of bioactivities.In these reported diisoprenyl-cyclohexene/ane-type meroterpenoids,only three dimers were identified.The discovery of the two new dimers added members of this rare class of meroterpenoids.