Aptameric SERS sensor for Hg^(2+) analysis using silver nanoparticles

摘要

Aptamer-silver nanoparticles(AgNPs) based surface-enhanced Raman scattering(SERS) sensor has been developed for Hg^(2+) detection by employing the structure-switching aptamer in the presence of spermine.This simple method shows excellent sensitivity and selectivity owing to the sensitive SERS detection technique and high specificity of aptamer for binding Hg^(2+).