Synthesis of Chiral N-Ferrocenylmethylaminoalcohols and their Application in Enantioselective Addition of Diethylzinc to Aldehydes

摘要

Three chiral N-ferrocenylmethylaminoalcohols were synthesized from readily available natural L-valine, leucine and phenylanine, and used as chiral ligands in the enantioselective addition of diethylzinc to aldehydes.