Preparation and Adsorption Properties of PAM Based Adsorbents for Plasma Lipoproteins

摘要

Crosslinked macroporous polyacrylamide (PAM) was prepared with inverse phase suspension polymerization technique.After treatment with hydrazine,the polymer was functionalized with chloroacetic acid,trifluoroacetic acid diethylenetriaminepentaacetic acid (DEPAA),and maleic acid,respectively,and PAM based adsorbents beating carboxyl functional groups for low density lipoprotein (LDL) apheresis use were obtained.The blood compatibility and the adsorption properties for plasma lipoproteins of PAM based adsorbents were investigated.