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Preparation of Chitosan-coated Nylon Membranes and their Application as Affinity Membranes

         

摘要

Chitosan-coated nylon membranes which possess a large number of reactive groups of –CH2OH and –NH2 were prepared by coupling chitosan onto the nylon membrane. Then polylysine as ligand was also immobilized onto the composite membranes by 1, 1’-carbonyl- diimidazole activation to prepare affinity membranes for bilirubin adsorption. The results showed that these membranes exhibited high binding affinity capacities for bilirubin and the adsorption isotherm fitted the Freundlich model well.

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