Study on the Interaction of Pd-TMPyP with ctDNA by Solid-substrate Room Temperature Phosphorescence

摘要

The interaction between calf thymus DNA (ctDNA) and Pd (II) meso-tetrakis-(4-N-methyl pyridiniumyl) porphyrin (Pd-TMPyP) was investigated by steady solid-substrate roomtemperature phosphorescence (SS-RTP). The SS-RTP intensity and lifetime of Pd-TMPyPenhanced with the increasing ctDNA. The anion quenching experiment of Pd-TMPyP indicatedthat Pd-TMPyP intercalated into ctDNA, which was also approved by UV-Vis spectra.