A simple and convenient method for the synthesis of S-aryl phosphorothioates catalyzed by cesium hydroxide

摘要

In the presence of a catalytic amount of cesium hydroxide,the corresponding S-aryl phosphorothioates can be obtained by the reactions of dialkyl phosphites with diaryldisulfdes in excellent yields at room temperature,using DMSO as a solvent.The reaction mechanism was discussed.The method provides a new and expedient path for the preparation of S-aryl phosphorothioates.