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《中国化学快报:英文版》
>One-pot synthesis of pyrrolo1,2-aquinoxaline and pyrrolo1,2-apyrazine derivatives via the three-component reaction of 1,2-diamines, ethyl pyruvate and α-bromo ketones
One-pot synthesis of pyrrolo1,2-aquinoxaline and pyrrolo1,2-apyrazine derivatives via the three-component reaction of 1,2-diamines, ethyl pyruvate and α-bromo ketones
A simple synthetic protocol has been developed involving the three-component reaction between 1,2-diamines, ethyl pyruvate and a-bromo ketones in the presence of Fe Cl3 as a catalyst. A number of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives were synthesized in excellent yields using this protocol.
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