11-Mercaptoundecanoic acid functionalized gold nanoclusters as fluorescent probes for the sensitive detection of Cu2+ and Fe3+ ions

摘要

Metal ions are physiologically essential,but excessive metal ions may cause severe risk to plants and animals.Here,we prepared gold nanoclusters (Au NCs) protected by 11-mercaptoundecanoic acid (11-MUA),which have excellent fluorescence properties for the detection of metal ions.The results showed that the copper ions (Cu2+) and iron ions (Fe3+) in the solution have obvious quenching effect on the fluorescence intensity of Au NCs.The detection range of Fe3+ was 0.8-4.5 μmol/L (R2 =0.992) and 4.5-11.0 μmol/L (R2 =0.997).And Cu2+ has a lower linear range (0.1-1.0 μmol/L,R2 =0.993).When EDTA was added into the reaction system,it was observed that the quenching effect of Cu2+ and Fe3+ on Au NCs showed different phenomenon.Then,the effect of metal ions on the fluorescence of Au NCs was investigated.The selective detection of Cu2+ was achieved by EDTA masking of Fe3+.In addition,we realized the metal ions detection application of Au NCs in the serum