A minor arcutine-type C20-diterpenoid alkaloid iminium constituent of“fu zi”

摘要

A rare arcutine-type C_(20)-diterpenoid alkaloid, named aconicarmicharcutinium A and obtained as hydroxide(1) and trifluoroacetate(1a), was characterized as a minor constituent of "fu zi"(the lateral roots of Aconitum carmichaelii). The structures of 1 and 1a were elucidated by comprehensive analysis of spectroscopic data including^(19)F and 2D NMR experiments. Compounds 1 and 1a represent the first examples of the arcutine-type C_(20)-diterpenoid alkaloid iminium.