早期高压氧治疗对创伤性颅脑损伤患者认知功能的影响

摘要

Objective To explore the influence of early-stage hyperbaric oxygen treatment on cognitive function in pa-tients with traumatic brain injury. Methods Eighty patients treated in our hospital from January 2010 to December 2013 were selected and evenly divided into two groups,each group of 40 cases.In control group,symptomatic treatment and supporting therapy were applied,while in observation group,on the basis of the control group,after one week,hyper-baric oxygen was used.Scores of mini-mental state examination(MMSE)and activity of daily living(ADL)after treatment in both groups were compared.The prognosis after treatment of 3 months was recorded. Results The score of MMSE and ADL in observation group after treatment was higher than that before treatment and in control group respectively (P<0.05).The incidence rate of day and night inversion,anepia,abasia and memory loss after treatment of 3 months in obser-vation group was lower than that in control group respectively (P<0.05). Conclusion Early-stage hyperbaric oxygen in the treatment of traumatic brain injury can effectively improve patient’s cognitive function as well as quality of life.%目的：探讨早期高压氧治疗对创伤性颅脑损伤患者认知功能的影响。方法选择2010年1月~2013年12月收治患者80例分为两组，各40例，对照组实施对症支持处理，观察组则在此基础上于1周后，采用高压氧治疗，比较两组治疗后MMSE评分及ADL评分，并统计治疗3个月的预后情况。结果治疗后，观察组MMSE评分及ADL评分均高于治疗前及对照组(P<0.05)；观察组治疗后3个月的昼夜颠倒、言语不能、行走不能及记忆力丧失发生率均低于对照组(P<0.05)。结论早期高压氧治疗创伤性颅脑损伤患者能有效改善患者的认知功能，并提高其生活质量。