Objective To evaluate the palliative effect of~(89)SrCl_2on multiple metastatic bone-pain of malig-nant tumors. Methods The palliative effect and side effect in 126 patients with metastatic bone-pain of malignant tumors after intravenous~(89)SrCl_2were observed. Results The bone-pain disappeared or relieved in 103 patients after therapy. The completely effective rate was 81.7%. Bone scan showed that metastatic in 38 patients slowed down or vanished. The counts of leucocyte were decreased mildly in a few patients. The damage of liver and kidney was not observed after therapy. Conclusions The~(89)SrCl_2is effective for treating patients with metastatic bone-pain of carci-noma. The side-effect is mild and it can be applied repeatedly.%目的 评价~(89)SrCl_2治疗恶性肿瘤骨转移癌性骨痛的疗效.方法 回顾性分析126例恶性肿瘤骨转移癌导致骨痛患者的病例资料,对静脉注射~(89)SrCl_2后的镇痛作用及不良反应进行分析与总结.结果 治疗后骨痛消失或缓解103例,总有效率81.7%,治疗后骨显像显示,38例患者骨病灶缩小或消失,5例患者出现白细胞一过性减低,肝、肾功能无变化.结论 ~(89)SrCl_2对恶性肿瘤骨转移导致的骨痛有较好的疗效,药物不良反应小,可重复用药.
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