脑梗死患者血压分期目标调控的研究

摘要

Objective To explore the results in patients with cerebral infarction treated by blood pressure stage target control.Methods Four hundred cases of cerebral infarction patients were divided into treatment group and control group.The basic secondary prevention measures were the same in two groups.Blood pressure stage target control was implemented in treatment group and blood pressure level around 140/85 mm Hg was targeted in the control group.After five years of follow-up,the function of health level and terminal events were assessed.Results After follow-up ended,regarding the cases of function health level classification of level 0,level 1,level 2,level 3,level 4,level 5,level 6 and recurrence of cerebral infarction,the treatment group were 96,62,18,12,4,5,3and 20 cases; and the control group were 44,24,26,25,22,29,30 and 78 cases.The function of health level in treatment group was higher than that in the control group ( P ＜ 0.05 ) and terminal events in treatment group were lower than those in the control group(P ＜ 0.05).Conclusion Blood pressure stage target control for patients with cerebral infarction is effective.%目的 探讨脑梗死患者血压分期目标调控的效果.方法 将400例脑梗死患者完全随机分为研究组和对照组,各200例.2组基本二级预防措施一致.研究组实施血压分期目标调控,对照组目标血压在140/85 mm Hg左右.随访至2010年12月,对2组患者的机能健康水平和终点事件分别进行评定.结果 至2010年12月,按牛津残障评分表进行机能健康水平分级,研究组0级96例(48.0％)、1级62例(31.0％)、2级18例(9.0％)、3级12例(6.0％)、4级4例(2.0％)、5级5例(2.5％)、6级3例(1.5％),再发梗死20例(10.0％)；对照组0级44例(22.0％)、1级24例(12.0％)、2级26例(13.0％)、3级25例(12.5％)、4级22例(11.0％)、5级29例(14.5％)、6级30例(15.0％),再发梗死78例(39.0％).2组机能健康水平比较,研究组优于对照组,差异有统计学意义(P＜0.05).2组再发梗死情况比较,研究组少于对照组,差异亦有统计学意义(P＜0.05).结论 脑梗死患者血压的分期目标调控有效.