中药复方大承气汤胃管灌注结合临床常规内科方法治疗肠梗阻的效果分析

摘要

Objective To explore the effect of intragastric infusion with Chinese medicine compound Dachengqi decoction combined with conventional medical treatment in treating intestinal obstruction.Methods Totally 42 patients with intestinal obstruction from May 2013 to February 2014 were randomly divided into routine group (21 cases) receiving conventional medical treatment and traditional Chinese medicine (TCM) group (21 cases) receiving intragastric infusion with Dachengqi decoction combined with traditional medical treatment.The efficacy was recorded;the drainage of gastrointestinal decompression 3 d after treatment,anus exhaust time,duration of hospitalization,recurrence rate during 12-month follow-up and incidence of adverse reactions were compared between groups.Results The total effective rate in TCM group was significantly higher than that in routine group [76.2％ (16/21) vs 52.4％ (11/21)] (P ＜ 0.05).The drainage of gastrointestinal decompression 3 d after treatment,anal exhaust time,duration of hospitalization and recurrence rate during 12-month gastrointestinal decompression and drain during the period of 12 months follow-up recurrence rate of TCM group were significantly lower/shorter than thoe in routine group [(242±21) ml vs (386±23) ml,(3.2±1.0) d vs (4.2±1.0) d,(7.0±1.1) d vs (8.1 ± 1.0) d,4.8％ (1/21) vs 23.8％ (5/21)] (P ＜ 0.05).The incidence of adverse reactions in TCM group was significantly lower than that in routine group [28.6％ (6/21) vs 81.0％ (17/21)];the severity of adverse reactions in TCM group was significantly lower than that in routine group (P ＜0.05).Conclusion Combining intragastric infusion and Chinese medicine compound Dachengqi decoction can improve the effect of conventional medical treatment in treating intestinal obstruction,with less adverse reactions.%目的 探讨中药复方大承气汤胃管灌注联合临床常规内科治疗肠梗阻的效果.方法 选取2013年5月至2014年2月于陕西省榆林市中医医院就诊的肠梗阻患者42例,按照入院时的单双号分成常规组和中药组,各21例.常规组采用临床常规内科方法治疗;中药组在常规组治疗基础上使用中药复方大承气汤胃管灌注治疗.观察并记录2组的疗效,记录患者治疗后第3天胃肠减压引流量、肛门排气时间、住院时间、随访12个月的复发率和治疗期间不良反应发生情况.结果 药物治疗后,中药组总有效率明显高于常规组[76.2％(16/21)比52.4％(11/21)]、胃肠减压引流量、肛门排气时间、住院时间以及在12个月随访期间内的复发率均明显低于常规组[(242±21) ml比(386±23)ml、(3.2±1.0)d比(4.2±1.0)d、(7.0±1.1)d比(8.1±1.0)d、4.8％(1/21)比23.8％ (5/21)](均P＜0.05).中药组不良反应发生率明显低于常规组[28.6％ (6/21)比81.0％(17/21)],不良反应严重程度明显低于常规组(P＜0.05).结论 使用复方大承气汤和临床常规内科方法治疗肠梗阻,能够提高患者治疗效果,且不良反应较小.