肝硬化并发肝源性糖尿病的临床表现及预后影响

摘要

Objective To explore clinical manifestations and prognostic effect of liver cirrhosis complicated with hepatic diabetes.Methods 120 patients with liver cirrhosis who were admitted to our hospital from December 2013 to December 2014 were retrospectively analyzed and researched. They were allocated to the liver cirrhosis complicated with hepatic diabetes group and the liver cirrhosis without diabetes group according to the diagnosis of diabetes. Complication, clinical characteristic, liver functional classification, prognostic effect and outcome of patients were analyzed and compared.Results The incidence of liver cirrhosis complicated with hepatic diabetes was 35.8%. In the liver cirrhosis complicated with hepatic diabetes group, incidence of complications (hepatic encephalopathy, gastrointestinal bleeding and electrolyte disorder) was higher and hospitalization time was longer compared with the liver cirrhosis without diabetes group (P<0.05). And mortality rate of the liver cirrhosis complicated with hepatic diabetes group was higher than that of the liver cirrhosis without diabetes group(P<0.05). ConclusionLiver cirrhosis complicated with hepatic diabetes has a high rate of complications and prolonged hospitalization time which do great harm to life quality of patients. It needs to be concerned in clinic.%目的：对肝硬化并发肝源性糖尿病的临床表现及预后影响进行深讨。方法对于2013年12月～2014年12月在我院就诊的肝硬化患者120例进行回顾性分析研究。根据诊断患者是否患有糖尿病将其分为肝硬化并发肝源性糖尿病以及肝硬化无糖尿病组，对各病例的并发症、临床特点、肝功能分级、预后影响以及转归等进行分析比较。结果肝硬化并发肝源性糖尿病发生率为35.8％（43/120）。与无糖尿病组相比，肝硬化并发肝源性糖尿病组并发症（如肝性脑病、消化道出血和电解质紊乱）发生率高且住院时间长（P＜0.05）。且死亡率方面肝硬化并发肝源性糖尿病组也比无糖尿病组高（P＜0.05）。结论肝硬化并发肝源性糖尿病并发症发生率高，住院天数延长，对患者生活质量带来极大危害，应在临床上加以重视。