目的:探讨血清瘦素水平与乳腺癌发病的相关性.方法:选择50例乳腺癌患者(观察组)和50例健康女性(对照组)均采用酶联免疫吸附试验(ELISA)法检测血清瘦素水平.结果:观察组血清瘦素水平[(19.25±8.65)μg/L]明显高于对照组[(6.25±4.25)μg/L],差异有统计学意义(P<0.05);不同临床分期乳腺癌患者的血清瘦素水平差异无统计学意义(P>0.05).结论:乳腺癌作为一个发病率高且危害较大的恶性肿瘤,血清瘦素水平升高在乳腺癌的发病中可能起重要作用,从而为乳腺癌的防治工作提供参考.%Objective: To discuss the correlation between breast cancer and serum leptin level. Methods: 50 cases of patients with breast cancer (observation group) and 50 cases of healthy women (control group) were selected and the serum leptin level was detected by enzyme - linked immunosorbent assay (ELBA). Results: The serum leptin level of the observation group [(19.25 ± 8.65)μg/L] was significantly higher than that of the control group [(6.25 ±4.25)μg/L], the difference was statistically significant (P<0.05). However, patients with breast cancer of different clinical stages, the serum leptin levels showed no significant difference (P<0.05). Conclusion: Breast cancer is a malignant tumor with high incidence and great harm, the serum leptin level may paly an important role in the incidence of breast cancer, which can provide a reference for prevention and treatment of breast cancer.
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