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糖尿病肾病的早期诊断方法研究进展

     

摘要

糖尿病肾病是糖尿病常见的微血管并发症之一.常规尿检查不易早期发现,一旦发生临床糖尿病肾病,尚缺乏有效方法控制其发展,大多数患者数年后转为慢性肾功能衰竭,威胁着糖尿病患者的生命.因此早期诊断可以早期干预、延缓糖尿病肾病的发展.目前认为,在早期糖尿病肾病诊断中临床指标有尿微量白蛋白、尿N-乙酰-β-D氨基葡萄糖苷酶、β2-微球蛋白等.%Diabetic nephropathy is one of the most common microvascular complications of diabetes. Early detection with the conventional urine test is unlikely. In the event of clinical diabetic nephropathy, there is still a lack of effective methods to control its development. Most patients are developped into chronic renal failure a few years later, threatening lives of patients with diabetes. Therefore, early diagnosis can intervene and delay the development of diabetic nephropathy. Currently considered clinical indicators in the early diagnosis of diabetic nephropathy include urinary microalbumin, urinary N-acetyl-P-fl-glucosaminidase, P2-microglobulin and so on.

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