目的:探讨中医序贯疗法治疗溃疡性结肠炎的临床疗效.方法:选取2009年1月~2010年5月在我院就诊的100例溃疡性结肠炎患者,将其随机分为对照组与治疗组,每组各50例.治疗组先依据湿热内蕴证进行清肠化湿,病情缓解后依据脾胃虚弱程度进行清肠扶正中药序贯疗法治疗;对照组采用美沙拉嗪进行治疗,对比其临床疗效.结果:经过6个月的治疗后,治疗组复发率为6%(3/50),对照组复发率为28%(14/50),治疗组的疗效优于对照组,差异有统计学意义(P<0.05).治疗组不良反应发生率为2%(1/50),对照组不良反应发生率为8%(4/50),治疗组不良反应发生率低于对照组,差异有统计学意义(P<0.05).结论:中医序贯疗法治疗溃疡性结肠炎,疗效显著,值得临床应用推广.%Objective: To investigate the clinical efficacy of traditional Chinese medicine sequential therapy in the treat -ment of ulcerative colitis. Methods: 100 patients in our hospital from January 2009 to May 2010 were random divided into treatment group (50 cases) and control group (50 cases). The control group was given Mesalazine, while the patients of the treatment group were given the methods of clearing intestines and resolving dampness according to damp-heat syndrome, and were given traditional Chinese medicine sequential therapy to clear intestines and strengthen healthy energy according to the degree in weakness of spleen and stomach when patients slightly alleviated. Clinical effects of two groups were com -pared. Results: The recurrence rates of treatment group and control group were 6% (3/50) and 28% (14/50) respectively after 6 months treatment, with significant difference between two groups (P<0.05). The incidence of adverse reactions of treatment group and control group were 2% (1/50) and 8% (4/50) respectively after therapy, with significant difference between two groups (P<0.05). Conclusion: Traditional Chinese medicine sequential therapy can be a promising method for ulcerative colitis, and is worthy to use in clinic.
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