Objective To observe the clinical effect and safety of Duhuo Jisheng Decoction combined with lumbar manipulation in the treatment of lumbar disc herniation (LDH).Methods 90 cases of patients with LDH were enrolled,who came from Beijing Changping Hospital of Integrated Chinese and Western Medicine from March 2015 to June 2016.All the patients were randomly divided into experimental group (45 cases) and control group (45 cases) by random number table.The experimental group was treated by Duhuo Jisheng Decoction combined with lumbar manipulation,the control group was treated by Diclofenac Sodium Enteric-coated Tablets and lumbar traction.The evaluation indicators were Japanese orthopaedic association (JOA) backache total scores,visual analogue scale (VAS) of lumbocrural pain,hepatorenal function,adverse events or adverse reactions.Results After treatment for two weeks,the JOA backache total scores in the two groups were all higher than those before treatment,the VAS scores of lumbocrural pain in the two groups were all lower than those before treatment,the differences were all highly statistically significant (P <0.01).After treatment,the JOA backache total scores in the experimental group were significantly higher than those of control group (P < 0.01),the VAS scores of lumbocrural pain in the experimental group were significantly lower than those of control group (P < 0.05).During the study,the safety was good in both groups.Conclusion Duhuo Jisheng Decoction combined with lumbar manipulation in the treatment of LDH can improve the clinical symptoms and signs of patients,the short-term curative effect is reliable,and the safety is good.%目的 观察独活寄生汤联合腰椎手法治疗腰椎间盘突出症(LDH)的临床效果和安全性.方法 纳入90例LDH患者,均来自北京市昌平区中西医结合医院骨伤科门诊,就诊时间为2015年3月~2016年6月,采用随机数字表法将患者随机分为试验组(45例)和对照组(45例),试验组应用独活寄生汤联合腰椎手法治疗,对照组应用双氯芬酸钠肠溶片联合腰椎牵引治疗.评价指标为日本骨科学会(JOA)腰痛总分、腰腿痛视觉模拟评分(VAS)、肝肾功能、不良事件/不良反应.结果 治疗2周后,两组JOA腰痛总分均显著高于治疗前,腰腿痛VAS评分均显著低于治疗前,差异均有高度统计学意义(P<0.01).试验组治疗后JOA腰痛总分显著高于对照组(P<o.o1),腰腿痛VAS评分明显低于对照组(P<0.05).试验过程中两组患者安全性良好.结论 独活寄生汤联合腰椎手法治疗LDH可改善患者临床症状、体征,短期疗效显著,安全性较好.
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机译:Conferenza di Consenso。 Ossigeno-Ozono Terapia Nel Trattamento Delle Lombosciatalgie da Ernia Discale Con Tecnica Iniettiva Intramuscolare paravertebrale Istituto superiore di sanita Roma 20 Novembre 2006(共识会议。腰椎椎旁肌内注射氧气 - 臭氧引起的腰椎间盘突出症.Istituto superioe di sanita。罗马,2006年11月20日)