青光眼与健康眼的视网膜血氧饱和度比较

摘要

目的 探讨青光眼患部的视网膜血氧饱和度变化.方法 选取2011年5月-2016年3月于四川省攀枝花市中心医院收治的的青光眼患者80例共139眼(观察组)和同期到该院接受检查的健康者80例共146眼(对照组),比较两组的视网膜血氧饱和度和视野指标,并进行相关性分析.结果 两组的视网膜静脉血氧饱和度比较无差异(P >0.05).观察组的视网膜动脉血氧饱和度和动静脉血氧饱和度差值低于对照组(P <0.05).观察组的平均视网膜光敏感度低于对照组,平均视野缺损度高于对照组(P <0.05).动静脉血氧饱和度差值与平均视网膜光敏感度呈正相关(P <0.05),与平均视野缺损度呈负相关(P <0.05).结论 青光眼患部视网膜动脉血氧饱和度降低,视网膜静脉血氧饱和度无明显变化,且与视网膜光敏感度和视野缺损度密切相关.%Objective?To study the changes of retinal oxygen saturation in patients with glaucoma.?Methods?In this study, 80 cases of glaucoma patients (139 eyes) and 80 healthy subjects (control group) in our hospital from May 2011 to March 2016 were examined retrospectively. The retina blood oxygen saturation and visual field index of the two groups were compared, and the correlations were analyzed.?Results?There was no significant difference in retinal venous oxygen saturation between the two groups (P > 0.05). The retinal arterial oxygen saturation and arteriovenous oxygen saturation difference were significantly lower in the case group than in the control group (P < 0.05). The mean retinal light sensitivity in the case group was significantly lower than that in the control group (P < 0.05). The average visual field defect in the case group was significantly higher than that in the control group (P < 0.05). The arteriovenous oxygen saturation difference was positively correlated with the mean retinal light sensitivity, but negatively correlated with the average visual field defect (P < 0.05).?Conclusions?The oxygen saturation of retinal artery in glaucoma sufferers is significantly decreased, while the oxygen saturation of retinal vein has no obvious change. And the arteriovenous oxygen saturation difference is closely related to mean retinal light sensitivity and the average visual field defect.