308 nm准分子激光联合人胎盘提取物治疗白癜风疗效评价

摘要

目的：：评价308 nm准分子激光联合人胎盘提取物治疗白癜风的疗效。方法：220例白癜风患者随机分为研究组和对照组，每组110例。研究组患者(进展期29例，稳定期81例；寻常型95例，节段型15例)给予308 nm准分子激光照射联合人胎盘提取物外涂；对照组(进展期29例，稳定期81例；寻常型93例，节段型17例)仅照射308 nm准分子激光。治疗后4周评价疗效。结果：研究组治疗显效率为81.81％高于对照组的63.63％( P<0.05)。研究组寻常型、肢端部位及稳定期白癜风显效率分别为85.26％、70％及86.42％高于对照组的66.67％、27.27％及69.14％(均P<0.05)；两组节段型及进展期治疗显效率无明显差别( P>0.05)。结论：308 nm准分子激光联合人胎盘提取物对寻常型、稳定期以及肢端型白癜风有较好的疗效。%Objective:To assess the therapeutic efficacy of 308 nm excimer laser in combination with hu-man placenta extract in the treatment of vitiligo. Methods:Two hundred and twenty patients with vitiligo were divided into the treatment group and control group, 110 patients in each group. The patients in the treatment group ( 29 patients in positive stage and 81patients in stable stage, 95 patients of vulgaris type and 15 patients of segmental type) were treated with 308 nm excimer laser in combination with human placenta extract. The patients in the control group ( 29 patients in positive stage and 81patients in stable stage, 93 patients of vulgar-is type and 17 patients of segmental type) were treated with308 nm excimer laser alone. The efficacy was as-sessed after treatment for four weeks. Results:The significant effective rates in the treatment group and control group were 81.8% and 63.63%, with a significant difference ( P<0.05) . The significant efficiency in the pa-tients of vulgaris type, acrofacial vitiligo and stable stage was 85.26%, 70% and 86.42%, which was higher than those in the control group (66.67%, 27.7% and 69.14%). There was no significant difference in the effi-ciency in segmental type and positive stage between the two groups ( P>0.05) . Conclusion:308 nm excimer laser in combination with human placenta extract is more effective than 308 nm excimer laser alone in the treatment of vulgaris vitiligo, especially for stable and acrofacial vitiligo.