超声支气管镜下局部注入顺铂治疗晚期中央型肺癌并气道外压性狭窄的研究(附10例报告)

摘要

Objective To explore the clinical application value of bronchoscopic endobronchial ultrasound (EBUS) guided intratumoral injection of Cisplatin in treatment of airway stenosis caused by advanced central lung cancer. Methods The clinical data of 10 cases of airway stenosis caused by advanced central lung cancer between Nov 2015 and Jan 2017 were analyzed retrospectively. Results 10 cases airway stenosis caused by advanced central lung cancer received EBUS guided intratumoral injection of Cisplatin treatment. Assessed by bronchoscopic, there were 8 cases of patients showed favorable effects after the treatment; Assessed by CT scan, 6 cases showed effects;And 8 cases relieved dyspnea. Conclusion EBUS guided intratumoral injection of Cisplatin in treatment of airway stenosis caused by advanced central lung cancer have some effect.%目的 探讨超声支气管镜下局部注入顺铂治疗晚期中央型肺癌并气道外压性狭窄的临床应用价值.方法 回顾性调查2015年11月-2017年1月该科10例超声支气管镜下局部注入顺铂治疗晚期中央型肺癌并气道外压性狭窄的临床资料,分析其缓解率、受益率和不良反应.结果 超声支气管镜下局部注入顺铂治疗晚期中央型肺癌并气道外压性狭窄10例,支气管镜下判断8例有效,CT判断6例有效,呼吸困难症状改善8例.结论 超声支气管镜下局部注入顺铂治疗晚期中央型肺癌并气道外压性狭窄有一定的疗效.