Objective To compare the clinical curative effect of endoscopic retrograde cholangio-pancreatography (ERCP) and percutaneous transhepatic cholangial drainage (PTCD) in treatment of malignant obstructive jaundice. Methods Clinical data of 97 patients with malignant obstructive jaundice were collected and analyzed retrospectively, includs 54 patients in ERCP group and 43 patients in PTCD group. The clinical curative effect, postoperative complications, comfort score and hospitalization time and costs were compared between the two groups. Results The symptoms improved compared with preoperative. The total remission rate of jaundice in ERCP group and PTCD group was 77.78％ vs 79.07％, and the remission rate of high obstructive jaundice was 55.00％, vs 89.29％, and the remission rate of low obstruction jaundice was 91.18％, vs 60.00％.There was significant difference between the two groups (P < 0.05); The incidence of postoperative complications in ERCP group and PTCD group was 37.04％ vs 16.28％. There was significant difference between the two groups (P < 0.05); The comfort scale of ERCP group and PTCD group was (15.13 ± 3.89) points vs (16.60 ± 3.15) points. There was significant difference between the two groups (P < 0.05); The hospitalization time of ERCP group and PTCD group were (8.74 ± 4.94) days vs (11.12 ± 4.82) days, and the hospitalization costs were (22.70 ± 6.30) thousand yuan vs (21.90 ± 3.40) thousand yuan. Conclusion Satisfactory clinical curative effect for patients with malignant obstructive jaundice can be derived from both ERCP and PTCD. The treatment of ERCP has more advantages than PTCD in patients with low obstruction, while PTCD is better than ERCP in patients with high obstruction. But ERCP group is better than PTCD in comfort score and shorter in hospitalization time. There is no obvious difference on hospitalization costs.%目的 对比经内镜逆行胰胆管造影术(ERCP)和经皮肝穿刺胆道引流术(PTCD)治疗恶性梗阻性黄疸的临床疗效.方法 回顾性分析湖北民族学院附属民大医院肝胆胰外科恶性梗阻性黄疸患者97例,其中ERCP组54例和PTCD组43例.对比两组患者临床疗效、术后并发症、舒适度评分、住院天数和费用.结果 ①两组患者症状较术前改善,生化指标均下降,ERCP组和PTCD组黄疸总缓解率为77.78％ 和79.07％,高位梗阻黄疸缓解率为55.00％ 和89.29％,低位梗阻黄疸缓解率为91.18％ 和60.00％,差异有统计学意义(P<0.05);②ERCP组和PTCD组术后并发症发生率为37.04％ 和16.28％,差异有统计学意义(P<0.05);③ERCP组和PTCD组舒适度量表评分为(15.13±3.89)和(16.60±3.15)分,差异有统计学意义(P<0.05);④ERCP组和PTCD组住院时间分别为(8.74±4.94)和(11.12±4.82)d,差异有统计学意义(P<0.05),住院费用分别为(2.27±0.63)和(2.19±0.34)万元,差异无统计学意义(P>0.05).结论 ERCP和PTCD对恶性梗阻性黄疸的治疗均可获得满意的临床疗效,ERCP对低位梗阻患者治疗优于PTCD,PTCD对高位梗阻患者治疗优于ERCP.ERCP并发症高于PTCD,舒适评分优于PTCD且住院时间短,两者在费用上无明显差异.
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