噻托溴铵联合肺康复措施对稳定期慢阻肺患者肺动脉压力和生活质量的影响

摘要

ObjectiveTo evaluate the effect of tiotropium combined with pulmonary rehabilitation on pulmonary arterial pressure and quality of life in patients with stable chronic obstructive pulmonary disease(COPD).Methods 86 cases of COPD patients with pulmonary hypertension were randomly divided into two groups. The control group(46 cases)was treated with pulmonary rehabilitation measures,and the observation group(40 cases)was treated with the use of the combination of tiotropium and pulmonary rehabilitation measures.Results After treatment of 6 months,there were significant differences between the PASP,6MWD,quality of life score of the two groups(P<0.05). ConclusionTiotropium combined with pulmonary rehabilitation measures is effective to treat stable COPD patients with pulmonary arterial hypertension.%目的：评价噻托溴铵联合肺康复措施对稳定期慢阻肺（COPD）患者肺动脉压力和生活质量的影响。方法86例稳定期慢阻肺合并肺动脉高压患者分为两组，对照组46例实施肺康复措施，观察组40例采用噻托溴铵联合肺康复措施治疗。结果治疗6月后两组PASP、6MWD、生活质量评分相比，P＜0.05。结论噻托溴铵联合肺康复措施治疗稳定期COPD合并肺动脉高压效果显著。