目的：探讨分析针对性手术联合新辅助化疗治疗乳腺癌的临床效果。方法方便选取该院2011年1月—2013年6月收治的110例乳腺癌患者随机分为对照组与观察组，对照组55例患者行针对性手术治疗，观察组55例患者行针对性手术治疗联合新辅助化疗，对比两组患者的手术效果、术后并发症发生率及复发率等。结果观察组手术时间及住院时间明显短于对照组，术中出血量明显少于对照组(P<0.05)。观察组治疗有效率为81.82%，明显高于对照组的50.91%(P<0.05)。观察组并发症发生率为7.27%，明显低于对照组的32.73%(P<0.05)。所有患者均经2年随访，观察组复发率为3.64%，明显低于对照组的10.91%(P<0.05)。结论针对性手术治疗联合新辅助化疗治疗乳腺癌有着创伤小、不良反应少、患者功能恢复快等优点，在临床上值得推广应用。%Objective To study the clinical effect of combining specific operation and neoadjuvant chemotherapy in treating breast cancer. Methods Convenient selection randomly divided 110 cases with breast cancer in our hospital from January 2011 to June 2013 into control group and experimental group, 55 cases in control group were treated by specific operation, 55 cases in experimental group were treated by specific operation and neoadjuvant chemotherapy, compared the operation effect, complication rate, and recurrence rate. Results The operation period and hospital stays of experimental group were much shorter than that of control group, the blood loss during operation was less than that of control group (P<0.05). The clinical effect rate of experimental group was 81.82%, which was much higher than that of control group, 50.91%(P<0.05). The complication rate of experimental group was 7.27%, which was lower than that of control group, 32.73%(P<0.05). The recurrence rate of experimental group was 3.64%, which was much lower than that of control group, 10.91%(P<0.05). Con-clusion Combining specific operation and neoadjuvant chemotherapy in treating breast cancer have many advantages, like little injury, less complication, fast recovery, et al, is worthy of clinical applicaition.
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