目的：为了进一步观察药物联合血液透析单超脱水对原发性肾病伴重度浮肿的临床治疗效果。方法根据我院2012年1月～2015年12月所收治的52例原发性肾病伴重度浮肿患者的临床治疗资料，随机将全部患者分为对照组（糖皮质激素等）和治疗组（药物联合血液透析单超脱水），每组各有患者26例，治疗期限均为1～4周，对比两组患者浮肿消退、肾功能、血清蛋白、尿蛋白等指标的变化情况。结果对比两组患者浮肿消退、肾功能、血清蛋白、尿蛋白等指标的变化情况治疗组优于对照组，对比结果差异具有统计学意义（P ＜0.05）。另外，治疗组患者无并发症发生。结论原发性肾病伴重度浮肿是临床常见病症，会给患者的治疗计划带来严重影响，严重者甚至会危及生命，药物联合血液透析单超脱水法是有效的治疗手段，且并发症较少、浮肿消退快。%Objective To observe the effect of drug combined with hemodialysis in the treatment of primary nephritic syndrome with severe edema. Methods According to the data of 52 patients in our hospital from January 2012 and December 2015 primary nephritic syndrome accompanied with severe edema, were randomly divided to control group (glucocorticoids) and treatment group (drug combined with hemodialysis single super dehydration), 26 cases in each group, were from 1 to 4 weeks. Results Compared with the two groups of patients with edema subsided, renal function, serum protein, urinary protein and other indicators of changes in the treatment group was significantly better than the control group, the results showed significant statistical difference (P<0.05). Patients in the treatment group had no complications. Conclusion Primary nephrotic syndrome with severe edema is a common disease in clinic, and will have a serious impact on the patient's treatment plan, severe cases may even life-threatening, drug combined with hemodialysis single super dehydration is effective treatment and less complications, edema subsided quickly.
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