产时缩宫素联合葡萄糖酸钙和卡前列素氨丁三醇防治产后出血的效果分析

摘要

Objective To discuss the effects of oxytocin and calcium gluconate combined with carboprost tromethamine in preventing postpartum hemorrhage in clinical. Methods A total of 172 cases of maternal patients with high risk factors of postpartum hemorrhage were selected and divided into control group and observation group from January 2012 to August 2014, 86 cases in each group. Patients in control group were given oxytocin and calcium gluconate in childbirth time, and patients in observation group were given carboprost tromethamine on the basis of control group in childbirth time. Postpartum hemorrhage, serum Ca2+ concentration and Hb changes were compared between the two groups, and the incidence of adverse reactions in the two groups were recorded.Results Observation group postpartum hemorrhage rate, postpartum hemorrhage was better than the control group (P < 0.05), observation group maternalserum Ca2+ concentration and Hb change value is better than the control group (P<0.05). And the difference in adverse reactions between two groups was not significant (P>0.05).Conclusion Oxytocin, calcium gluconate and carboprost tromethamine has great clinical effects in preventing and controlling postpartum hemorrhage, which makes it worth for clinical application.%目的：探讨联合应用缩宫素、葡萄糖酸钙和卡前列素氨丁三醇防治剖宫产后出血的临床效果。方法将2012年1月～2014年8月收治的172例有高危出血因素的产妇随机分为对照组和观察组各86例。对照组产时给予缩宫素、葡萄糖酸钙，观察组产时给予缩宫素、葡萄糖酸钙和卡前列素氨丁三醇。比较两组产妇产后的出血情况、血清Ca2+浓度和Hb变化值，并记录两组不良反应的发生情况。结果观察组产妇产后出血发生率、产后出血量优于对照组产妇（P＜0.05）；观察组产妇血清Ca2+浓度和Hb变化值优于对照组（P＜0.05）；观察组产妇不良反应发生率与对照组产妇相比差异无统计学意义（P＞0.05）。结论产时给予缩宫素、葡萄糖酸钙和卡前列素氨丁三醇对预防和控制产后出血有明显效果，且无严重不良反应发生。