细菌耐药性：正悄然威胁人类和动物的健康

摘要

The phenomenon of antimicrobial resistance(AMR)is an ancient mechanism that,after the industrializa-tion of antimicrobials(AM),became ubiquitous in its origin and detrimental consequences and cannot be confront-ed without a multidisciplinary approach. THE European Union and the international community have created initiatives to fight AMR and,different AMR surveillance programs have detected an alarming increase in AMR across the globe. This,together with the slow progress in the discovery of new antibiotic and other alternatives AM,represent a serious threat to global health. Lower percentages of AMR observed in the North of Europe are associated to the prudent use of AM and holistic approaches in the control of infections. These results that are a motive for optimism in the fight against AMR using comprehensive and multidisciplinary approaches.%自抗菌药产业化以来，细菌耐药性问题就无处不在并造成严重的不良后果，研究发现只有多学科参与，采取综合措施才能应对此类问题。欧盟和国际社会提出了应对耐药性动议，多个耐药性监测项目发现全球对耐药性的关切不断增强。此外，新型抗生素及其替代品的研究进展缓慢，耐药性正严重威胁着人类健康。北欧因谨慎使用抗菌药及其综合防控措施行之有效，因而耐药性问题比较小。总的来说，多学科参与，采取综合性措施应对耐药性问题的效果相当乐观。