采用微波辐射法合成了乙酰水杨酸,考察了反应时间、辐射功率、pH 值、反应底物比(水杨酸与乙酸类衍生物的物质的量比)等因素对反应的影响,并研究了反应动力学。确定最佳反应条件为:反应时间70 s、辐射功率450 W、pH 值5.4、反应底物比1∶2,推算了宏观动力学方程并计算得到表观反应活化能为75.60 kJ·mol-1。%Acetylsalicylic acid was synthesized by microwave irradiation.The effect of several factors,such as reaction time,irradiation power,pH value and reactant ratio(molar ratio of salicylic acid to acetic acid deriva-tive)on reaction were investigated,and reaction kinetics was studied.The optimal conditions were obtained as follows:reaction time of 70 s,irradiation power of 450 W,pH value of 5.4,reactant ratio of 1∶2.The kinetics e-quation was obtained and Arrhenius activation energy was 75.60 kJ·mol-1 .
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