The GSTP1 gene variant rs1695 is not associated with an increased risk of multiple sclerosis

摘要

We analyzed the allelic and genotypic frequencies of the glutathione-S-transferase P1 (GSTP1) rs1695 single nucleotide polymorphism (SNP) in 290 patients with multiple sclerosis (MS) and in 310 healthy controls.We found no significant association between the rs1695 variant and MS.Among MS patients, there was no relationship between the rs1695 variant and either gender, clinical type of MS or the age of onset of MS.These results suggest that the GSTP1 rs1695 polymorphism is not a risk factor for MS.