Engineered trimeric ACE2 binds viral spike protein and locks it in'Three-up'conformation to potently inhibit SARS-CoV-2 infection

著录项

• 来源
  《细胞研究（英文版） 》 |2021年第1期|98-100|共3页
• 作者

  Liang Guo; Xia Cai; Shibo Jiang; Youhua Xie; Qiang Zhou; Lu Lu; Bobo Dang; Wenwen Bi; Xinling Wang; Wei Xu; Renhong Yan; Yuanyuan Zhang; Kai Zhao; Yaning Li; Mingfeng Zhang;

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• 作者单位

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

  Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) School of Basic Medical Sciences and Biosafety Level 3 Laboratory Fudan University Shanghai 200032 China;

  Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) School of Basic Medical Sciences and Biosafety Level 3 Laboratory Fudan University Shanghai 200032 China;

  Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) School of Basic Medical Sciences and Biosafety Level 3 Laboratory Fudan University Shanghai 200032 China;

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

  Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) School of Basic Medical Sciences and Biosafety Level 3 Laboratory Fudan University Shanghai 200032 China;

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

  Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) School of Basic Medical Sciences and Biosafety Level 3 Laboratory Fudan University Shanghai 200032 China;

  Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) School of Basic Medical Sciences and Biosafety Level 3 Laboratory Fudan University Shanghai 200032 China;

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

  Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University Hangzhou Zhejiang 310024 China;

  Center for Infectious Disease Research Westlake Laboratory of Life Sciences and Biomedicine Hangzhou Zhejiang 310024 China;

  Institute of Biology Westlake Institute for Advanced Study Hangzhou Zhejiang 310024 China;

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• 正文语种 eng
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